Similar content being viewed by others Subjects Introduction Glutathione (GSH) deficiency is one of the earliest biochemical perturbations in Parkinsons disease (PD), 1,2 leading to the hypothesis that GSH supplementation may have therapeutic value in alleviating PD symptoms or modifying progression
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In contrast, siRNA-mediated downregulations of zDHHCs result in stronger changes in the overall S-palmitoylation, thus confirming that these closely related Nt 7 sequences are differentially modified by PM- and Golgi-associated PATs