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Alternatively (and this is the approach I take for many patients), if you are experiencing significant symptomatic improvement then you can just continue to take the B12 shots indefinitely

Importantly, if you have unexpectedly high B12 levels without taking supplements or receiving injections, this warrants GP review as it may indicate underlying liver disease, kidney disease, or certain blood disorders

Alcohol use: Alcohol can increase inflammatory responses and disrupt gut health

Swelling can temporarily obscure results and even make the treated area appear larger before it improves

Notably, harsh dehydration steps were not performed to minimize the damage to the original biofilm structure

In addition, expression of IGF-1 and IGF-2 mRNA increased following acute deletion of IR in primary chondrocytes (Figure 4d and 4e)