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Selenium and redox signaling

[MDPI] Mar M, Morales A, Colell A, Garca-Ruiz C, Fernndez-Checa JC

Acknowledgements This work was financially supported by the National Key Research and Development Program of China (2024YFA0917900), the National Natural Science Foundation of China (22178173, 22408166), the Natural Science Found of Jiangsu Province (BK20240539), the Jiangsu Basic Research Center for Synthetic Biology (BK20233003), the China Postdoctoral Science Foundation (2024M751420, GZC20231119), and the State Key Laboratory of Materials-Oriented Chemical Engineering (SKL-MCE-24A10)

IGF-1R Binding and Downstream Signalling IGF-1 LR3 remains a full agonist of the IGF-1 receptor, with very low affinity for IGFBPs making it more potent than unmodified IGF-1 in cell culture and pre-clinical models

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