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Kerner, J

Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH), consisting of 44 amino acids with a structural modification at its N-terminal end

And all of these can be true at the same time

During discontinuation and washout, a structured plan to minimize weight regain and glycaemic deterioration is advisablefor example, reinforcing dietary/physical-activity targets and, where clinically indicated, using metformin as a maintenance optionso that metabolic stability is preserved before ART initiation

DOI: 10.1016/S0140-6736(22)02033-5

However, other randomized controlled trials have not found any benefit of citicoline treatment in the management of acute ischemic stroke (98, 99), including a recent trial evaluating its effects when provided immediately following endovascular thrombectomy (i.e., recanalization therapy) and continued for 42 days (100)