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A phase Ib study of linsitinib (OSI-906), a dual inhibitor of IGF-1R and IR tyrosine kinase, in combination with everolimus as treatment for patients with refractory metastatic colorectal cancer
Reader KL, Cox NR, Stanton JA, Juengel JL
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Upon receipt, transfer the vial to the refrigerator promptly
The metabolic effects that promote glucose uptake acutely can, with chronic exposure, lead to cells becoming less responsive to insulin's signals
Administered directly into muscle tissue, B12 injections bypass the need for absorption in the gastrointestinal tract, making them a highly effective method for increasing B12 levels in the body
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