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However, they need to make sure the supplement provides acceptable amounts of vitamin B12 made from high-quality ingredients
Reconstitution techniques
PMID: 41966639 | doi:10.1007/s40279-026-02437-0
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Vegans, older adults, and people with digestive conditions are at higher risk
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
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