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doi: 10.1007/s12602-019-9514-3 23 LiuYTianXHeBHoangTKTaylorCMBlanchardEet al

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Some small studies suggest that L-carnitine supplementation during calorie restriction may improve the ratio of fat loss to lean mass loss, but the effect sizes are small and not all studies agree

If side effects are problematic, your doctor can discuss alternatives, including: Dose adjustment or slower titration Switching to a different GLP-1 receptor agonist Alternative diabetes medications with different mechanisms of action Additional treatments to manage specific symptoms According to NICE guidance on type 2 diabetes management (NG28), treatment decisions should be individualised, balancing efficacy, side effects, patient preferences, and overall quality of life

Neurobeachin ( NBEA ) Is a Novel Gene Associated with GLP 1 Receptor Agonist Associated Weight Loss. Diabetes, Obesity and Metabolism , vol