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Over a 28-day period, lean WT mice treated with either compound exhibited increased body weight, replicating results seen in the shorter 14-day study

(CJC1295 human study

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Rare but serious risks include pancreatitis, gallbladder disease, acute kidney injury (secondary to dehydration from GI effects), and a theoretical thyroid C-cell tumor risk based on rodent data that has not been confirmed in human post-marketing surveillance

Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired