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although human relevance remains uncertain, patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2) are generally advised not to use GLP-1 RAs
But it also creates new forms of risk concerning needle safety, unsettling patient-practitioner relationships via unregulated use, and the subversion of public health messages that groups such as Cancer Council Australia have worked for decades to promote.
If you are weighing convenience, safety, cost, and results, this guide breaks down what the science and regulators currently say about oral GLP-1 approaches both approved pills and the unregulated "drops" sold online compared to established injectable therapies
Others are more experimental or marketed as wellness products, without sufficient evidence to guide treatment
JAMA Psychiatry 72 , 1421 (2015)
