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In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12

Within the Vitamin B complex, there are several members, including Vitamin B1 (thiamine), Vitamin B2 (riboflavin), Vitamin B3 (niacin), Vitamin B5 (pantothenic acid), Vitamin B6 (pyridoxine), Vitamin B7 (biotin), Vitamin B9 (folate), and notably, vitamin B12 (cobalamin)

Additionally, B12 is involved in energy metabolism, aiding in the conversion of food into energy, and has implications for mood regulation through its role in neurotransmitter synthesis

Pediatrics 2001;108(3):776-789

Bariatric surgery Restricted stomach = reduced B12