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After background subtraction of corresponding solvents, the observed ellipticity in millidegrees was converted to mean residual ellipticity [ MRE , degcm 2 dmol -1 ] using the following equation (millidegrees mean residual weight)/(path length in millimeters concentration in mgmL -1 ) ( f a ) of SR18 at 222 was calculated as the ratio of [ 222 ]experimental to [ 222 ]theoretical, as described here ( 2.5 Dynamic Light Scattering (DLS) studies SR18 dissolved in filtered 1X PBS (pH 7.4) and 20% TFE to a final concentration of 100 M was subjected to DLS measurement to gauge its hydrodynamic size and particle size distribution, using bovine serum albumin as the reference

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