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Rajman, L., Chwalek, K

JAMA 2022;327:534-45.ArticlePubMedPMC 129

No extreme muscle loss

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It also participates in energy metabolism, specifically in the conversion of food into usable cellular energy

Exercise-Induced Oxidative Stress Intense or prolonged exercise generates substantial oxidative stress through increased oxygen consumption and metabolic rate, increased mitochondrial electron leakage producing reactive oxygen species, recruitment of inflammatory immune cells to exercising muscles, and mechanical stress on tissues producing oxidative damage