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Journal of Applied Physiology (Bethesda, Md.: 1985) , 110 (3), 774780
Tirzepatide and cardiovascular disease A previous study has shown that tirzepatide can protect human cardiomyocytes by effectively ameliorating apoptosis, fibrosis, and hypertrophy when exposed to high glucose
The reduction in -cell mass in patients with T2DM can be attributed to -cell apoptosis triggered by multiple factors, including islet amyloid deposition, lipotoxicity, glucotoxicity, and inflammation (You et al., 2022)
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Research in this area is still in its infancy, with clinical trials just getting started
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