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There are three main types of diabetes covered in this factsheet

GLP-1 stands for glucagon-like peptide-1, a hormone naturally produced in the gut that tells our bodies when weve eaten, helping regulate blood sugar and appetite

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Matouskova P, Bartikova H, Bousova I, Levorova L, Szotakova B, Skalova L (2015) Drug-metabolizing and antioxidant enzymes in monosodium L-glutamate obese mice

The GLP-1 (treatment) cohort was comprised of individuals who (i) had no prior history of GLP-1 use, (ii) initiated GLP-1 medications from January 2019 onwards with the prescription originating from a primary care provider or endocrinologist, and (iii) had medication orders indicating a minimum duration of 12 months of prescriptions

Monitoring and Management Protocol Patients taking Wegovy alongside any opioid should be monitored across four domains: GI function, pain adequacy, hydration and electrolytes, and sedation