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Rather than acting within a single pathway, these compounds are studied for their roles across interconnected systems, where inflammatory signaling, tissue adaptation, and immune modulation form a continuous network

Biochem J 476(7):11911203 Yousuf PY, Hakeem KUR, Chandna R, Ahmad P (2012) Role of glutathione reductase in plant abiotic stress

The clinical significance of understanding these peptides lies in their potential to address pathological conditions where conventional therapies may demonstrate limited efficacy

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465,466 This activation is predominantly mediated through the disruption of the Kelch-like ECH-associated protein 1 (KEAP1) - NRF2 interaction (oxidation of KEAP1 Cys151, Cys273, and Cys288), 29 facilitating the translocation of NRF2 into the nucleus

[PMID: 31045123] PubMed record related to this compound for laboratory literature review