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[] Insulin, for instance, requires multiple daily injections, which can be challenging for patients, [] and while metformin is generally well-tolerated, its safety profile remains somewhat controversial, as it crosses the placenta

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Considering the association of SARS-CoV-2 and ACE2, Patel et al

485 Primary Prevention: Emerging Evidence Clinical trials and observational studies are also examining the potential role of colchicine in primary prevention of thrombotic events (ie, in people who have never had a cardiovascular emergency or known chronic coronary artery disease)

It has been FDA-approved for patients with type 2 diabetes since 2017