Hentze MW, Muckenthaler MU, Andrews NC (2004) Balancing acts: molecular control of mammalian iron metabolism
Women tend to gain weight in their lower body, especially in the hips, thighs, and buttocks
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Common Side Effects: Injection site reactions (erythema, pruritus, pain) Arthralgia (joint pain) Peripheral edema (fluid retention) Myalgia (muscle pain) Pain in extremities Important Warnings: Contraindicated in active malignancy: GH/IGF-1 promote cell proliferation Contraindicated in pregnancy: Category X Glucose monitoring required: May affect glucose metabolism IGF-1 monitoring recommended: To assess response and safety Rare but Serious: Potential tumor growth stimulation Glucose intolerance/diabetes exacerbation Hypersensitivity reactions Fluid retention complications Regulatory Status United States: FDA approved (2010) for HIV-associated lipodystrophy
Diabetes Therapy: Research, Treatment and Education of Diabetes and Related Disorders, 12 (1), 143157
There is no threshold under which this substance is not prohibited