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From the Lab Related Blog Posts Apr 13, 2026 About blank

Ferroptosis suppressor protein 1 (FSP1) was identified almost simultaneously by Bersuker et al

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In contrast, the PDI ALS-mutants (D292N and R300H) lack this redox activity and were not protective against ALS phenotypes, further confirming the importance of the redox activity of PDI in ALS (Parakh et al., 2020)