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Furthermore, gene-editing therapies targeting Angiopoietin-like 3 (ANGPTL3) 399,400 and LDLR 401,402 have entered the preclinical stage, highlighting the broader potential of gene-editing-based lipid-lowering strategies, and long-acting therapies that provide stable and durable lipid-lowering effects could further reduce the risk of cardiovascular events
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For women seeking pregnancy who have PCOS and insulin resistance, GLP-1 therapy represents a targeted approach to treating the underlying metabolic driver of infertility
doi:10.1097/CORR.0000000000002805
Experts say the available research suggests that the drug has promising potential
It decreases leptin, the satiety hormone, by a similar amount
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