Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes
The utilization of lactate as an energy source allows neurons to maintain their ATP levels even when aerobic glycolysis is compromised by NAD depletion (200)
The generation of acetyl-CoA in the nucleus is necessary for the acetylation of histone proteins, particularly histone H3
Diabetes Care 40 , 6976 (2017)
En general, los efectos beneficiosos del AR GLP-1 sobre los resultados cardiovasculares en pacientes de alto riesgo con DT2 probablemente se explican por una combinacin de efectos metablicos, vasculares, antitrombticos y antiinflamatorios
Excess adiposity, particularly in the context of obesity, is associated with increased mechanical load during physical activity, sleep-disordered breathing, and systemic inflammationall of which contribute to fatigue