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Interestingly, a small trial in 30 premenopausal women found that daily multivitamin supplementation for ten weeks did not improve overall mood, but when the supplement also contained 7 mg/day of zinc (RDA=8 mg/day), the authors noted significant improvements in two components of POMS: the anger-hostility and the depression-dejection scores (140)

Additionally, it is crucial to recognize the existence of ME/CFS subtypes, such as those arising post-infection versus other causes, as well as the fluctuating nature and intensity of symptoms

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