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Some evidence suggests that individuals with impaired glucose tolerance may exhibit different GLP-1 responses to dietary stimuli compared to metabolically healthy individuals, though specific data regarding allulose in this context remain limited

Additionally, conflicting findings suggest that prolonged metformin treatment may exacerbate AD pathology in genetically susceptible models, increasing -amyloid accumulation, tau phosphorylation, and synaptic dysfunction 92

Skin Sensitivity: Mild irritation or warmth may occur due to the absorption-enhanced base

& Zeisberg, E

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Coghlan MP, OFarrell L, Showalter AD, et al