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In the SURPASS-2 trial, patients with obesity and T2D who received tirzeapatide (5 mg weekly) achieved greater HbA1c and body weight reductions than those receiving semaglutide (1 mg weekly) during the 40 week study (64) despite comparable putative GLP-1R occupancy at these doses (47)

3.2 In vivo studies An in vivo study sought to assess the impact of goji berry extract ( Lycium barbarum ) on DED, specifically emphasizing its anti-inflammatory and antioxidant characteristics by applying Schirmers test, tear break-up time (BUT) measurement and keratoconjunctival fluorescein staining

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