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this information supports a more informed conversation about maintaining treatment efficacy and adjusting dosing if needed

Cholinesterase positivity may be present and often Meissners corpuscle-like structures are found (Figs 25.50, 25.51)

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5 patients provided blood at both untreated and treated status, 2 patients provided blood only in the untreated state, and 2 patients provided blood only in the treated state (Supplementary Table 1)

With deterioration of the culture environment (bound in hydrogel) or external stimulation (laser irradiation), AST gradually accumulates, turning HEA cells red (RHEA) and endowing them with a potent capacity to modulate the wound microenvironment

To test for differentially activated regulons across treatments, a linear mixed-effects model was constructed with the SCENIC regulon activity score as dependent variable, treatment and time point as independent variables with interaction effects, and mouse and sequencing pool as random effects