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Overall, 1,767 patients were randomized to semaglutide and 1,766 to placebo in an 8-week dose-escalation regimen that began with 0.25 mg per week for 4 weeks and maxed out at 1.0 mg per week throughout the remainder of the treatment period

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We should monitor blood glucose in patients who have over-injected, and think about GLP-1As in patients with unexplained hypoglycaemia even if they are not diabetic

If vomiting, severe abdominal pain, fainting, confusion, repeated low glucose readings, or signs of dehydration occur, seek medical guidance promptly

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