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AOD-9604 failed its largest trial
Serious Considerations / Risk Notes Melanotan II is not FDA-approved and is not regulated as a standard medical therapy
Its a results-driven product
Medicare covers GLP-1s for $50/month starting July 2026 For decades, a legal exclusion blocked Medicare from covering drugs used for anorexia, weight loss, or weight gain. That sentence is the reason a Medicare beneficiary with a BMI of 38 could not get Wegovy through their drug plan (unless they also had established cardiovascular disease)
Hansen, A
The blood pressure-lowering effect appears to be driven primarily by weight loss (patients in the STEP trials lost 10-15% of body weight), though improvements in insulin sensitivity and vascular function may also contribute
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