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In human AD brains, mitochondrial dysfunction correlates with the burden of A and tau

Emerging nanotechnology approaches, including polymeric nanoparticles and lipid-based delivery systems, show promise in enhancing SFN stability, prolonging circulation time, and improving tumor-specific delivery (94, 102)

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A peptide that survives the stomach intact still faces intestinal brush-border peptidases and first-pass hepatic metabolism before it can reach systemic circulation

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