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Exenatide Exenatide (Byetta and Bydureon, AstraZeneca), originally discovered as Exendin-4 (Ex-4) in the saliva of the gila monster (Heloderma suspectum), is a synthetic peptide with 39 amino acids (129)

Lorundrostat, another (ASI) aldosterone synthase inhibitor, is already in regulatory review, suggesting this may become an entirely new therapeutic class

Better insulin sensitivity can prevent the excessive storage of fat and support weight loss efforts

Strategies to minimize symptoms include slower titration schedules, maintaining adequate hydration, and consuming smaller, more frequent meals

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