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10.1093/jn/130.4.1016S 65

If bowel transit and microbiome balance are poor, hormones recirculate improperly, metabolic inflammation increases, and many interventions fail to stick

This process results in both reduced serotonin production as well as increased production of quinolinic acid, which functions as an agonist of the NMDA glutamate receptor (53)

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Much of the bodys magnesium is stored in the skeleton