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However, glutathione levels are quickly depleted during viral infections
September 20, 2022
The role of oxidative stress in the COVID-19 disease may involve recognition of the viral S-protein by angiotensin converting enzyme-2 (ACE2) receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production (Kozlov et al., 2021)
Over time, this imbalance can contribute to fatigue, slower recovery, and increased cellular wear and tear
10.1016/j.lab.2004.10.006 202 TaleviA.CarrilloC.CominiM
