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Despite showing efficacy in ex vivo whole blood cultures, auranofin did not affect sputum culture conversion in early clinical trials [25]
furthermore, CR also reduced the expression of proapoptotic genes Bcl-xS/Bcl-xL, mitochondrial translocation of BAX, release of cytochrome c into cytosol, and caspase-9 activation (Niemann et al., )
Works as an antioxidant
Its molecular weight is 401.91 Da (with copper)
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