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We included parallel group randomised controlled trials in adults with type 2 diabetes in the traditional pairwise meta-analysis if they compared dipeptidyl peptidase-4 inhibitors with placebo or non-incretin drugs, and we included them in the network meta-analysis if they compared dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors with one another or with other antidiabetes drugs, placebo, or standard care

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Wegovy was approved to treat obesity in 2021