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Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
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To obtain the hematocrit-corrected platelet count (X) we used the following formula: X = (h1xp1 / HxP) x 100, wherein each symbol denotes the following: h1: hematocrit of the sample, p1: platelet count of the sample, H: mean hematocrit value of the normal range in healthy animals (= 0.435), P: mean platelet count value of the normal range in healthy animals (= 875)
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2 Other studies suggest GLP-1s may slightly improve mood or lower self-harm risk, likely tied to their effect on the brain's reward system
Where results are borderline, measurement of methylmalonic acid (MMA) or holotranscobalamin (active B12) may help clarify the picture, as recommended in NICE CKS guidance on B12 and folate deficiency anaemia
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