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From a practical perspective, this means that if retatrutide is eventually approved for use in obesity and diabetes, most patients can expect side effects to be manageable and temporary
These are consistent with other GLP-1 medications and were generally mild
STEP-5 is the longest of the STEP trials and spanned 104 weeks at 2.4mg/weekly and reported a favorable safety profile with no serious safety concerns
There is a large population of woman, specifically those in their perimenopause and menopause years who are overweight, but don't meet the strict BMI requirements
The early weeks are the hardest
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