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Pharmacol Res 1995;31:67-72

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No human subjects experienced any of the adverse effects commonly associated with exogenous human growth hormone therapy

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The degradation routes do not even belong to the same branch of chemistry: the peptides degrade by hydrolysis, isomerization and oxidation, while the copper complex changes by ligand exchange, by reduction of the metal, and by displacement of copper by any competing binder that reaches it

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Glutathione peroxidase activity is neuroprotective in models of Huntington's disease

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