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GHK-Cu additionally downregulates scar formation and fibrotic processes, suppresses harmful cytokines and signal transduction pathways (such as TGF-?1/Smad), and supports angiogenesis and stem cell differentiation

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10.1074/jbc.270.3.1230 107 WangY.HuangJ.SunY.StubbsD.HeJ.LiW.et al (2021)

The peptide still distributes systemically from a local injection, so you get both targeted and whole-body effects

Tang, F.M