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Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism
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Albumin has a plasma half-life of approximately 19 days partly through FcRn (neonatal Fc receptor) recycling semaglutide hijacks this mechanism to achieve its ~7-day half-life
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Loftsson, Cyclodextrins in Parenteral Formulations, Journal of Pharmaceutical Sciences, 2020, 1-11], Thus far, the use of cyclodextrins and cyclodextrin substituted derivatives in protein and peptide-based pharmaceutical formulations is limited