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( F ) Ex vivo 15LO1 protein expression correlates with intraepithelial cell GSH and GSH:GSSG ( n = 15)
It also stops the production of an enzyme called tyrosinase, which is involved in making melanin in the body
Nature 536 , 446450 (2016)
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Oxidative stress then accelerates the aggregation of -synuclein which subsequently binds and sequesters available GSH, creating a destructive feedback loop of protein misfolding and antioxidant loss (Hoepken et al., 2007)
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