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For instance, in several clinical and preclinical studies, SF counteracts several molecular abnormalities associated with autism spectrum disorder (ASD) that address reduced antioxidant capacity, enhanced oxidative stress, deficient glutathione synthesis, mitochondrial dysfunction, increased lipid peroxidation, and neuroinflammation (2)

This so-called incretin effect is attributed to the insulinotropic action of gut hormones, particularly: Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide 1 (GLP-1)

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It has been previously shown that both ghrelin (via GHSR1a) and the cannabinoids (via CB1) have orexigenic effects (Williams et al., 1998

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