Vet Immunol Immunopathol (2005) 108:7789
They found that iron, ACSL4, and MDA levels increased with increasing reperfusion time, with concomitant decreases in GPX4 levels, and deferoxamine treatment significantly ameliorated myocardial injury [88]
Ex vivo cytotoxicity assay NIH/3T3 cells, transfected with FAP protein, were used as target cells
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Researchers also distinguish reduced glutathione (GSH) from the disulfide GSSG, since it is the GSSG/2GSH ratio, not total glutathione, that Schafer and Buettner (Free Radical Biology and Medicine, 2001) established as the quantitative index of the cellular redox environment