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First-strand cDNA synthesis was performed with 1 g of total RNA in 20 l reactions using an iScript cDNA Synthesis Kit (Bio-Rad, Hercules, CA)

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The MHRA approved Wegovy 7.2 mg in January 2026, which produced an average weight loss of 20.7%, close to Mounjaros trial figures

A dose-response analysis across 39 randomised trials and 33,354 participants found that nausea risk rose fastest across the lowest doses, then showed a tendency to plateauing at highest dosages

While GLP-1 receptor agonists may offer some cardiovascular benefits, these effects are comparable to those achieved through bariatric surgery

Many countries impose duties on health supplements that can add 10-25% to the purchase price, making local alternatives more economical