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Factor in the rapid clearance mechanism, whereby nasally-applied drugs are cleared with a half-life of approximately 21 minutes, and its clear why only certain peptides can be used nasally
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In combination with intensive behavioral therapy for weight loss, individuals (total n=611) in another study (note: funded by Novo-Nordisk) on semaglutide lost 16% of their body weight compared to 5.7% in the placebo control group
