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Also, glutamate excitotoxicity NMDA-mediated intra-neuronal calcium overload elevates NO synthesis contributing to oxidative stress particularly the production of reactive nitrogen species which are able to cause defects in DNA and protein phosphorylation pathway (85)

Compounds that disrupt glucose-insulin dynamics typically create hunger patterns that interfere with dietary adherence

IV dosing in clinical practice varies based on indication, patient health status, and treatment goals

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In diabetes management, peptide-based drugs are frequently used in combination with small molecule medications such as metformin

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