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Neuroendocrine and sexual function studies examining MC4Rlinked pathways, arousal circuits, and hypothalamic signaling in preclinical models
According to the World Health Organization (WHO), approximately 890 million adults were living with obesity in 2022, while the International Diabetes Federation (IDF) estimated that 589 million adults aged 2079 years were living with diabetes globally in 2024, with the number expected to reach 853 million by 2050
AzaA8-treated mice exhibited a significant reduction in body weight over the 29-day treatment, losing on average 16% of their starting weight ( Fig
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