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The slower titration helps minimize gastrointestinal side effects though it delays reaching full therapeutic effect
Another imminent problem is that the GLP-1RAs that are currently used in the clinical setting are biological macromolecular peptide preparations, such as exenatide and liraglutide, with high production costs that limit their clinical application (231)
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10.1385/jcd:8:4:371 17 LincoffA
GLP1R Novo Nordisk and Eli Lilly are both experiencing GLP1R growth in the US thanks to Ozempic and Trulicity, whereas Victoza is declining
