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They exert anti-inflammatory effects by inhibiting HDAC and upregulating suppressor of cytokine signaling 3, thereby blocking the activation of NF-B and STAT3 signaling (Gao et al., 2013

Several sources of ROS have been identified during diabetes, including enhanced blood glucose flux through the polyol and hexosamine pathway, increased formation of advanced glycation end products, and activation of protein kinase C pathway (137, 138)

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Private insurance plans commonly cover between 50% and 100% of the cost