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These results represent a significant advancement over earlier GLP-1 receptor agonists and positioned tirzepatide as the clinical gold standard for pharmacological weight management heading into the mid-2020s
2017 Mar;95(3):323-333
Theoretically, combining AOD-9604 with beta-3 agonists (mirabegron) could amplify lipolytic effects, though no clinical reports describe this interaction
Important: increase fiber slowly
The trade-off: delayed gastric emptying can worsen reflux in some patients
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