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Therapeutic Research Protocol Dose: 2 mg Tesamorelin + 300 mcg Ipamorelin Duration: 12 16 weeks Frequency: Daily, evening administration Cycle Interval: 6 8 weeks off before repeating Goal / Description: Higher-dose protocol for visceral fat reduction and IGF-1 elevation studies

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Common side effects (reported by both men and women): Headaches: Mild headaches are the most frequently reported side effect during the first week or two

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GSH concentration is instead measured by either of two methods: by analysis of GS-NEM conjugates by HPLC in the same sample that is used to measure GSSG or, alternatively, by analysis of GSH by spectrophotometry (GSH recycling method) on one additional sample aliquot that has not been derivatized with NEM