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Participants also saw their fat-to-lean mass ratio drop from 0.93 to 0.70 , along with a reduction in waist circumference by 18.418.5 cm
Its a novel approach that combines different mechanisms to target multiple pathways involved in weight regulation
doi: 10.1590/s2175-97902019000217615
A tri-agonist developed by the same company targeting GIP-1R/GIPR/GCGR, retatrutide, demonstrated better weight loss effects in Phase 3 compared to tirzepatide
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