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Common strategies for extending the duration of GLP-1 RAs include: Amino Acid Sequence Optimization : Reducing rapid degradation by DPP-4 enzymes to extend the drug's half-life
Temperature excursions can degrade the peptide, reducing potency or creating breakdown products that may cause adverse reactions
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Metabolic Shifts As semaglutide influences how your body processes food and stores energy, it initiates metabolic changes
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